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Comparison of pathway analysis and constraint-based methods for cell factory design
BACKGROUND: Computational strain optimisation methods (CSOMs) have been successfully used to exploit genome-scale metabolic models, yielding strategies useful for allowing compound overproduction in metabolic cell factories. Minimal cut sets are particularly interesting since their definition allows...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585037/ https://www.ncbi.nlm.nih.gov/pubmed/31221092 http://dx.doi.org/10.1186/s12859-019-2934-y |