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Tumor-associated macrophage expression of interferon regulatory Factor-8 (IRF8) is a predictor of progression and patient survival in renal cell carcinoma

Tumor-associated macrophages have been well-characterized in solid malignancies, including renal cell carcinoma and generally correlate with poor prognosis. However, the molecular mechanisms which govern intratumoral macrophage behavior and patient outcome are unclear. Here, we investigated whether...

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Detalles Bibliográficos
Autores principales: Muhitch, Jason B., Hoffend, Nicholas C., Azabdaftari, Gissou, Miller, Austin, Bshara, Wiam, Morrison, Carl D., Schwaab, Thomas, Abrams, Scott I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585080/
https://www.ncbi.nlm.nih.gov/pubmed/31221219
http://dx.doi.org/10.1186/s40425-019-0630-0