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A novel method to establish glucocorticoid resistant acute lymphoblastic leukemia cell lines

BACKGROUND: Drug-resistant cell lines, established from drug-sensitive cell lines by drug exposure in vitro, are the most useful cancer models in studies on the mechanism of chemoresistance. However, the success rate of the traditional approaches to construct such cell lines is low because a long ti...

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Detalles Bibliográficos
Autores principales: Gu, Ling, Zhang, Ge, Zhang, Yanle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585113/
https://www.ncbi.nlm.nih.gov/pubmed/31221196
http://dx.doi.org/10.1186/s13046-019-1280-2