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A novel AR translational regulator lncRNA LBCS inhibits castration resistance of prostate cancer
BACKGROUND: Progression to a castration resistance state is the main cause of deaths in prostate cancer (PCa) patients. Androgen Receptor (AR) signaling plays the central role in progression of Castration Resistant Prostate Cancer (CRPC), therefore understanding the mechanisms of AR activation in th...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585145/ https://www.ncbi.nlm.nih.gov/pubmed/31221168 http://dx.doi.org/10.1186/s12943-019-1037-8 |