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A novel AR translational regulator lncRNA LBCS inhibits castration resistance of prostate cancer

BACKGROUND: Progression to a castration resistance state is the main cause of deaths in prostate cancer (PCa) patients. Androgen Receptor (AR) signaling plays the central role in progression of Castration Resistant Prostate Cancer (CRPC), therefore understanding the mechanisms of AR activation in th...

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Detalles Bibliográficos
Autores principales: Gu, Peng, Chen, Xu, Xie, Ruihui, Xie, Weibin, Huang, Li, Dong, Wen, Han, Jinli, Liu, Xiaodong, Shen, Jihong, Huang, Jian, Lin, Tianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585145/
https://www.ncbi.nlm.nih.gov/pubmed/31221168
http://dx.doi.org/10.1186/s12943-019-1037-8