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Intrinsic Spine Dynamics Are Critical for Recurrent Network Learning in Models With and Without Autism Spectrum Disorder

It is often assumed that Hebbian synaptic plasticity forms a cell assembly, a mutually interacting group of neurons that encodes memory. However, in recurrently connected networks with pure Hebbian plasticity, cell assemblies typically diverge or fade under ongoing changes of synaptic strength. Prev...

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Detalles Bibliográficos
Autores principales: Humble, James, Hiratsuka, Kazuhiro, Kasai, Haruo, Toyoizumi, Taro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585147/
https://www.ncbi.nlm.nih.gov/pubmed/31263407
http://dx.doi.org/10.3389/fncom.2019.00038