A novel mechanism of action of ketoconazole: inhibition of the NorA efflux pump system and biofilm formation in multidrug-resistant Staphylococcus aureus

Background: The rapid emergence of antimicrobial resistance among Gram-positive organisms, especially staphylococci, has become a serious clinical challenge. Efflux machinery and biofilm formation are considered two of the main causes of antimicrobial resistance and therapy failure. Aim: Our study a...

Descripción completa

Detalles Bibliográficos
Autores principales: Abd El-Baky, Rehab M, Sandle, Tim, John, James, Abuo-Rahma, Gamal El-Din AA, Hetta, Helal F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585162/
https://www.ncbi.nlm.nih.gov/pubmed/31354319
http://dx.doi.org/10.2147/IDR.S201124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585162/
https://www.ncbi.nlm.nih.gov/pubmed/31354319
http://dx.doi.org/10.2147/IDR.S201124

Ejemplares similares