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A novel mechanism of action of ketoconazole: inhibition of the NorA efflux pump system and biofilm formation in multidrug-resistant Staphylococcus aureus

Background: The rapid emergence of antimicrobial resistance among Gram-positive organisms, especially staphylococci, has become a serious clinical challenge. Efflux machinery and biofilm formation are considered two of the main causes of antimicrobial resistance and therapy failure. Aim: Our study a...

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Detalles Bibliográficos
Autores principales:	Abd El-Baky, Rehab M, Sandle, Tim, John, James, Abuo-Rahma, Gamal El-Din AA, Hetta, Helal F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585162/ https://www.ncbi.nlm.nih.gov/pubmed/31354319 http://dx.doi.org/10.2147/IDR.S201124

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