A Free Radical Scavenger Ameliorates Teratogenic Activity of a DNA Hypomethylating Hematological Therapeutic

The spin-trap free radical scavenger N-tert-butyl-α-phenylnitron (PBN) ameliorated effects of several teratogens involving reactive oxygen species (ROS). We investigated for the first time whether PBN could ameliorate teratogenesis induced by a DNA hypomethylating hematological therapeutic 5-azacyti...

Descripción completa

Detalles Bibliográficos
Autores principales: Sobočan, Nikola, Katušić Bojanac, Ana, Sinčić, Nino, Himelreich-Perić, Marta, Krasić, Jure, Majić, Željka, Jurić-Lekić, Gordana, Šerman, Ljiljana, Vlahović, Maja, Ježek, Davor, Bulić-Jakuš, Floriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Original Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585171/
https://www.ncbi.nlm.nih.gov/pubmed/30672391
http://dx.doi.org/10.1089/scd.2018.0194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585171/
https://www.ncbi.nlm.nih.gov/pubmed/30672391
http://dx.doi.org/10.1089/scd.2018.0194

Ejemplares similares