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Identification of myeloid cells in the human enthesis as the main source of local IL-23 production

OBJECTIVE: We investigated whether the normal human spinal enthesis contained resident myeloid cell populations, capable of producing pivotal proinflammatory cytokines including tumour necrosis factor (TNF) and interleukin (IL)-23 and determined whether these could be modified by PDE4 inhibition. ME...

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Detalles Bibliográficos
Autores principales: Bridgewood, Charlie, Watad, Abdulla, Russell, Tobias, Palmer, Timothy M, Marzo-Ortega, Helena, Khan, Almas, Millner, Peter A, Dunsmuir, Robert, Rao, Abhay, Loughenbury, Peter, Wittmann, Miriam, Cuthbert, Richard J, McGonagle, Dennis G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585277/
https://www.ncbi.nlm.nih.gov/pubmed/31018959
http://dx.doi.org/10.1136/annrheumdis-2018-214944