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Low-density granulocytes activate T cells and demonstrate a non-suppressive role in systemic lupus erythematosus

OBJECTIVES: The presence of proinflammatory low-density granulocytes (LDG) has been demonstrated in autoimmune and infectious diseases. Recently, regulatory neutrophilic polymorphonuclear myeloid-derived suppressor cells (PMN-MDSC) were identified in systemic lupus erythematosus (SLE). Because LDG a...

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Detalles Bibliográficos
Autores principales: Rahman, Saifur, Sagar, Divya, Hanna, Richard N, Lightfoot, Yaima L, Mistry, Pragnesh, Smith, Carolyne K, Manna, Zerai, Hasni, Sarfaraz, Siegel, Richard M, Sanjuan, Miguel A, Kolbeck, Roland, Kaplan, Mariana J, Casey, Kerry A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585283/
https://www.ncbi.nlm.nih.gov/pubmed/31040119
http://dx.doi.org/10.1136/annrheumdis-2018-214620