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Use of autologous (99m)Technetium-labelled neutrophils to quantify lung neutrophil clearance in COPD

RATIONALE: There is a need to develop imaging protocols which assess neutrophilic inflammation in the lung. AIM: To quantify whole lung neutrophil accumulation in (1) healthy volunteers (HV) following inhaled lipopolysaccharide (LPS) or saline and (2) patients with COPD using radiolabelled autologou...

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Detalles Bibliográficos
Autores principales: Tregay, Nicola, Begg, Malcolm, Cahn, Anthony, Farahi, Neda, Povey, Kathryn, Madhavan, Sujith, Simmonds, Rosalind, Gillett, Daniel, Solanki, Chandra, Wong, Anna, Maison, Joanna, Lennon, Mark, Bradley, Glyn, Jarvis, Emily, de Groot, Marius, Wilson, Fred, Babar, Judith, Peters, A Michael, Hessel, Edith M, Chilvers, Edwin R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585304/
https://www.ncbi.nlm.nih.gov/pubmed/30674586
http://dx.doi.org/10.1136/thoraxjnl-2018-212509