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Senescent Kidney Cells in Hypertensive Patients Release Urinary Extracellular Vesicles

BACKGROUND: Hypertension may be associated with renal cellular injury. Cells in distress release extracellular vesicles (EVs), and their numbers in urine may reflect renal injury. Cellular senescence, an irreversible growth arrest in response to a noxious milieu, is characterized by release of proin...

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Detalles Bibliográficos
Autores principales: Santelli, Adrian, Sun, In O., Eirin, Alfonso, Abumoawad, Abdelrhman M., Woollard, John R., Lerman, Amir, Textor, Stephen C., Puranik, Amrutesh S., Lerman, Lilach O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585370/
https://www.ncbi.nlm.nih.gov/pubmed/31433703
http://dx.doi.org/10.1161/JAHA.119.012584