mTORC1 Activation in Osteoclasts Prevents Bone Loss in a Mouse Model of Osteoporosis

The mechanistic/mammalian target of rapamycin (mTOR) is widely implicated in the pathogenesis of various diseases, including cancer, obesity, and cardiovascular disease. Bone homeostasis is maintained by the actions of bone-resorbing osteoclasts and bone-forming osteoblasts. An imbalance in the soph...

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Detalles Bibliográficos
Autores principales: Hiraiwa, Manami, Ozaki, Kakeru, Yamada, Takanori, Iezaki, Takashi, Park, Gyujin, Fukasawa, Kazuya, Horie, Tetsuhiro, Kamada, Hikari, Tokumura, Kazuya, Motono, Mei, Kaneda, Katsuyuki, Hinoi, Eiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585391/
https://www.ncbi.nlm.nih.gov/pubmed/31263418
http://dx.doi.org/10.3389/fphar.2019.00684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585391/
https://www.ncbi.nlm.nih.gov/pubmed/31263418
http://dx.doi.org/10.3389/fphar.2019.00684

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