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mTORC1 Activation in Osteoclasts Prevents Bone Loss in a Mouse Model of Osteoporosis
The mechanistic/mammalian target of rapamycin (mTOR) is widely implicated in the pathogenesis of various diseases, including cancer, obesity, and cardiovascular disease. Bone homeostasis is maintained by the actions of bone-resorbing osteoclasts and bone-forming osteoblasts. An imbalance in the soph...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585391/ https://www.ncbi.nlm.nih.gov/pubmed/31263418 http://dx.doi.org/10.3389/fphar.2019.00684 |