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Do Disruptions in the Circadian Timing System Contribute to Autonomic Dysfunction in Huntington’s Disease?

Huntington’s disease (HD) patients suffer from a progressive neurodegenerative disorder that inflicts both motor and non-motor symptoms. HD is caused by a CAG repeat expansion within the first exon of the huntingtin (HTT) gene that produces a polyglutamine repeat that leads to protein misfolding, so...

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Detalles Bibliográficos
Autores principales: Park, Saemi, Colwell, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: YJBM 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585531/
https://www.ncbi.nlm.nih.gov/pubmed/31249490