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Physiological effects of amyloid precursor protein and its derivatives on neural stem cell biology and signaling pathways involved

The pathological implication of amyloid precursor protein (APP) in Alzheimer’s disease has been widely documented due to its involvement in the generation of amyloid-β peptide. However, the physiological functions of APP are still poorly understood. APP is considered a multimodal protein due to its...

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Detalles Bibliográficos
Autores principales: Coronel, Raquel, Palmer, Charlotte, Bernabeu-Zornoza, Adela, Monteagudo, María, Rosca, Andreea, Zambrano, Alberto, Liste, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585543/
https://www.ncbi.nlm.nih.gov/pubmed/31169172
http://dx.doi.org/10.4103/1673-5374.257511