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Organocopper cross-coupling reaction for C–C bond formation on highly sterically hindered structures

We describe a powerful, broadly applicable cross-coupling protocol that enables carbon–carbon bond formation at highly sterically hindered carbon centers (both sp(2) and sp(3)) by employing organocopper reagents under palladium catalysis. Experimental studies and theoretical calculations indicated t...

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Detalles Bibliográficos
Autores principales: Oi, Miku, Takita, Ryo, Kanazawa, Junichiro, Muranaka, Atsuya, Wang, Chao, Uchiyama, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585593/
https://www.ncbi.nlm.nih.gov/pubmed/31360416
http://dx.doi.org/10.1039/c9sc00891h