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FAT1 is a novel upstream regulator of HIF1α and invasion of high grade glioma

The hypoxic microenvironment is an important contributor of glioblastoma (GBM) aggressiveness via HIF1α, while tumour inflammation is profoundly influenced by FAT Atypical Cadherin (FAT1). This study was designed to explore the functional interaction and significance of FAT1 and HIF1α under severe h...

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Detalles Bibliográficos
Autores principales: Madan, Evanka, Dikshit, Bhawana, Gowda, Srinivas H., Srivastava, Chitrangda, Sarkar, Chitra, Chattopadhyay, Parthaprasad, Sinha, Subrata, Chosdol, Kunzang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585695/
https://www.ncbi.nlm.nih.gov/pubmed/27536856
http://dx.doi.org/10.1002/ijc.30386