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VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases

V‐type immunoglobulin domain‐containing suppressor of T‐cell activation (VISTA) is a negative checkpoint regulator (NCR) involved in inhibition of T cell‐mediated immunity. Expression changes of other NCRs (PD‐1, PD‐L1/L2, CTLA‐4) during inflammation of the central nervous system (CNS) were previous...

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Detalles Bibliográficos
Autores principales: Borggrewe, Malte, Grit, Corien, Den Dunnen, Wilfred F. A., Burm, Saskia M., Bajramovic, Jeffrey J., Noelle, Randolph J., Eggen, Bart J. L., Laman, Jon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585704/
https://www.ncbi.nlm.nih.gov/pubmed/30306644
http://dx.doi.org/10.1002/glia.23517