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Evaluation of Food and Spherical Carbon Adsorbent Effects on the Pharmacokinetics of Roxadustat in Healthy Nonelderly Adult Male Japanese Subjects

Roxadustat is a hypoxia‐inducible factor prolyl hydroxylase inhibitor in late‐stage clinical development for the treatment of anemia in chronic kidney disease. Spherical carbon adsorbent (SCA) is used in patients with chronic kidney disease and has been shown to impact absorption of certain concomit...

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Detalles Bibliográficos
Autores principales: Shibata, Tomohisa, Nomura, Yuki, Takada, Akitsugu, Ueno, Mai, Katashima, Masataka, Yazawa, Rie, Furihata, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585706/
https://www.ncbi.nlm.nih.gov/pubmed/29966038
http://dx.doi.org/10.1002/cpdd.597