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Evaluation of Food and Spherical Carbon Adsorbent Effects on the Pharmacokinetics of Roxadustat in Healthy Nonelderly Adult Male Japanese Subjects
Roxadustat is a hypoxia‐inducible factor prolyl hydroxylase inhibitor in late‐stage clinical development for the treatment of anemia in chronic kidney disease. Spherical carbon adsorbent (SCA) is used in patients with chronic kidney disease and has been shown to impact absorption of certain concomit...
Autores principales: | Shibata, Tomohisa, Nomura, Yuki, Takada, Akitsugu, Ueno, Mai, Katashima, Masataka, Yazawa, Rie, Furihata, Kenichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585706/ https://www.ncbi.nlm.nih.gov/pubmed/29966038 http://dx.doi.org/10.1002/cpdd.597 |
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