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Protein catalyzed capture agents with tailored performance for in vitro and in vivo applications

We report on peptide‐based ligands matured through the protein catalyzed capture (PCC) agent method to tailor molecular binders for in vitro sensing/diagnostics and in vivo pharmacokinetics parameters. A vascular endothelial growth factor (VEGF) binding peptide and a peptide against the protective a...

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Detalles Bibliográficos
Autores principales: Coppock, Matthew B., Warner, Candice R., Dorsey, Brandi, Orlicki, Joshua A., Sarkes, Deborah A., Lai, Bert T., Pitram, Suresh M., Rohde, Rosemary D., Malette, Jacquie, Wilson, Jeré A., Kearney, Paul, Fang, Kenneth C., Law, Scott M., Candelario, Sherri L., Farrow, Blake, Finch, Amethist S., Agnew, Heather D., Heath, James R., Stratis‐Cullum, Dimitra N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585716/
https://www.ncbi.nlm.nih.gov/pubmed/27539157
http://dx.doi.org/10.1002/bip.22934