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Protein catalyzed capture agents with tailored performance for in vitro and in vivo applications
We report on peptide‐based ligands matured through the protein catalyzed capture (PCC) agent method to tailor molecular binders for in vitro sensing/diagnostics and in vivo pharmacokinetics parameters. A vascular endothelial growth factor (VEGF) binding peptide and a peptide against the protective a...
Autores principales: | Coppock, Matthew B., Warner, Candice R., Dorsey, Brandi, Orlicki, Joshua A., Sarkes, Deborah A., Lai, Bert T., Pitram, Suresh M., Rohde, Rosemary D., Malette, Jacquie, Wilson, Jeré A., Kearney, Paul, Fang, Kenneth C., Law, Scott M., Candelario, Sherri L., Farrow, Blake, Finch, Amethist S., Agnew, Heather D., Heath, James R., Stratis‐Cullum, Dimitra N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585716/ https://www.ncbi.nlm.nih.gov/pubmed/27539157 http://dx.doi.org/10.1002/bip.22934 |
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