Gene Expression and Pharmacodynamic Changes in 1,760 Systemic Lupus Erythematosus Patients From Two Phase III Trials of BAFF Blockade With Tabalumab

OBJECTIVE: To characterize baseline gene expression and pharmacodynamically induced changes in whole blood gene expression in 1,760 systemic lupus erythematosus (SLE) patients from 2 phase III, 52‐week, randomized, placebo‐controlled, double‐blind studies in which patients were treated with the BAFF...

Descripción completa

Detalles Bibliográficos
Autores principales: Hoffman, Robert W., Merrill, Joan T., Alarcón‐Riquelme, Marta M. E., Petri, Michelle, Dow, Ernst R., Nantz, Eric, Nisenbaum, Laura K., Schroeder, Krista M., Komocsar, Wendy J., Perumal, Narayanan B., Linnik, Matthew D., Airey, David C., Liu, Yushi, Rocha, Guilherme V., Higgs, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Systemic Lupus Erythematosus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585752/
https://www.ncbi.nlm.nih.gov/pubmed/27723281
http://dx.doi.org/10.1002/art.39950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585752/
https://www.ncbi.nlm.nih.gov/pubmed/27723281
http://dx.doi.org/10.1002/art.39950

Ejemplares similares