Data‐driven multi‐objective optimization via grid compatible simplex technique and desirability approach for challenging high throughput chromatography applications

Recently, a grid compatible Simplex variant has been demonstrated to identify optima consistently and rapidly in challenging high throughput (HT) applications in early bioprocess development. Here, this method is extended by deploying it to multi‐objective optimization problems. Three HT chromatogra...

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Detalles Bibliográficos
Autores principales: Konstantinidis, Spyridon, Welsh, John P., Titchener‐Hooker, Nigel J., Roush, David J., Velayudhan, Ajoy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
RESEARCH ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585819/
https://www.ncbi.nlm.nih.gov/pubmed/30294895
http://dx.doi.org/10.1002/btpr.2673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585819/
https://www.ncbi.nlm.nih.gov/pubmed/30294895
http://dx.doi.org/10.1002/btpr.2673

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