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Data‐driven multi‐objective optimization via grid compatible simplex technique and desirability approach for challenging high throughput chromatography applications
Recently, a grid compatible Simplex variant has been demonstrated to identify optima consistently and rapidly in challenging high throughput (HT) applications in early bioprocess development. Here, this method is extended by deploying it to multi‐objective optimization problems. Three HT chromatogra...
Autores principales: | Konstantinidis, Spyridon, Welsh, John P., Titchener‐Hooker, Nigel J., Roush, David J., Velayudhan, Ajoy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585819/ https://www.ncbi.nlm.nih.gov/pubmed/30294895 http://dx.doi.org/10.1002/btpr.2673 |
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