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Pharmacokinetics‐Pharmacodynamics of High‐Dose Ivermectin with Dihydroartemisinin‐Piperaquine on Mosquitocidal Activity and QT‐Prolongation (IVERMAL)

High‐dose ivermectin, co‐administered for 3 days with dihydroartemisinin‐piperaquine (DP), killed mosquitoes feeding on individuals for at least 28 days posttreatment in a recent trial (IVERMAL), whereas 7 days was predicted pretrial. The current study assessed the relationship between ivermectin bl...

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Detalles Bibliográficos
Autores principales: Smit, Menno R., Ochomo, Eric O., Waterhouse, David, Kwambai, Titus K., Abong'o, Bernard O., Bousema, Teun, Bayoh, Nabie M., Gimnig, John E., Samuels, Aaron M., Desai, Meghna R., Phillips‐Howard, Penelope A., Kariuki, Simon K., Wang, Duolao, ter Kuile, Feiko O., Ward, Stephen A., Aljayyoussi, Ghaith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585895/
https://www.ncbi.nlm.nih.gov/pubmed/30125353
http://dx.doi.org/10.1002/cpt.1219