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Pharmacokinetics‐Pharmacodynamics of High‐Dose Ivermectin with Dihydroartemisinin‐Piperaquine on Mosquitocidal Activity and QT‐Prolongation (IVERMAL)
High‐dose ivermectin, co‐administered for 3 days with dihydroartemisinin‐piperaquine (DP), killed mosquitoes feeding on individuals for at least 28 days posttreatment in a recent trial (IVERMAL), whereas 7 days was predicted pretrial. The current study assessed the relationship between ivermectin bl...
Autores principales: | Smit, Menno R., Ochomo, Eric O., Waterhouse, David, Kwambai, Titus K., Abong'o, Bernard O., Bousema, Teun, Bayoh, Nabie M., Gimnig, John E., Samuels, Aaron M., Desai, Meghna R., Phillips‐Howard, Penelope A., Kariuki, Simon K., Wang, Duolao, ter Kuile, Feiko O., Ward, Stephen A., Aljayyoussi, Ghaith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585895/ https://www.ncbi.nlm.nih.gov/pubmed/30125353 http://dx.doi.org/10.1002/cpt.1219 |
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