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Metronidazole concentration in the bloodstream following its topical application, at different concentration levels, on experimental skin wounds during healing by secondary intention

PURPOSE: To characterize qualitatively and quantitatively the absorption of metronidazole solution, in greater concentrations and for longer periods, when applied topically to an experimental open skin wound model. METHODS: An open skin wound, 2 cm in diameter and total skin thickness was prepared,...

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Detalles Bibliográficos
Autores principales: Sampaio, Cláudia Paraguaçu Pupo, Biondo-Simões, Maria de Lourdes Pessole, Trindade, Lilian Cristine Teixeira, Olandowski, Márcia, Matias, Jorge Eduardo Fouto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585925/
https://www.ncbi.nlm.nih.gov/pubmed/30785505
http://dx.doi.org/10.1590/s0102-865020190010000004