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Ramipril can alleviate the accumulation of renal mesangial matrix in rats with diabetic nephropathy by inhibiting insulin-like growth factor-1

PURPOSE: To investigate the impact of Ramipril (RAM) on the expressions of insulin-like growth factor-1 (IGF-1) and renal mesangial matrix (RMM) in rats with diabetic nephropathy (DN). METHODS: The Sprague Dawley rats were divided into normal control (NC) group (n = 12), DN group (n = 11), and DN+RA...

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Detalles Bibliográficos
Autores principales: Ren, Wei, Zhao, Chen, Wang, Yan, Fang, Yuan, Huang, Zhenzhen, Chen, Wei, Wang, Lihua, Hu, Wen, Wang, Ke, Ni, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585927/
https://www.ncbi.nlm.nih.gov/pubmed/30785508
http://dx.doi.org/10.1590/s0102-865020190010000007