Population Pharmacokinetics and Exposure‐Response Relationship of Intravenous and Subcutaneous Abatacept in Patients With Rheumatoid Arthritis

Abatacept population pharmacokinetics (PK) and exposure‐response (E‐R) models for selective efficacy end points were developed using phase 2 and 3 study data in patients with rheumatoid arthritis treated with abatacept (intravenous [IV] or subcutaneous [SC]), followed by simulations. Two efficacy en...

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Detalles Bibliográficos
Autores principales: Li, Xiaohui, Roy, Amit, Murthy, Bindu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Pharmacometrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585965/
https://www.ncbi.nlm.nih.gov/pubmed/30229926
http://dx.doi.org/10.1002/jcph.1308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585965/
https://www.ncbi.nlm.nih.gov/pubmed/30229926
http://dx.doi.org/10.1002/jcph.1308

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