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Developmental Toxicity Studies with Pregabalin in Rats: Significance of Alterations in Skull Bone Morphology
Pregabalin was administered to pregnant Wistar rats during organogenesis to evaluate potential developmental toxicity. In an embryo‐fetal development study, compared with controls, fetuses from pregabalin‐treated rats exhibited increased incidence of jugal fused to maxilla (pregabalin 1250 and 2500...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585975/ https://www.ncbi.nlm.nih.gov/pubmed/27074409 http://dx.doi.org/10.1002/bdrb.21175 |