Cargando…
Data Curation can Improve the Prediction Accuracy of Metabolic Intrinsic Clearance
A key consideration at the screening stages of drug discovery is in vitro metabolic stability, often measured in human liver microsomes. Computational prediction models can be built using a large quantity of experimental data available from public databases, but these databases typically contain dat...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586005/ https://www.ncbi.nlm.nih.gov/pubmed/30247811 http://dx.doi.org/10.1002/minf.201800086 |