Cargando…

Pharmacokinetics, Pharmacodynamics, and Tolerability of Concomitant Administration of Verinurad and Febuxostat in Healthy Male Volunteers

Verinurad (RDEA3170) is a selective uric acid reabsorption inhibitor in development for treatment of gout and asymptomatic hyperuricemia. This phase 1, single‐blind, multiple‐dose, drug‐drug interaction study evaluated the pharmacokinetics (PK), pharmacodynamics, and safety/tolerability of verinurad...

Descripción completa

Detalles Bibliográficos
Autores principales: Hall, Jesse, Gillen, Michael, Yang, Xiaojuan, Shen, Zancong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586034/
https://www.ncbi.nlm.nih.gov/pubmed/29688628
http://dx.doi.org/10.1002/cpdd.463