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HDL protects against myocardial ischemia reperfusion injury via miR-34b and miR-337 expression which requires STAT3

PURPOSE: High density lipoprotein (HDL) protects against myocardial infarction via mechanisms that remain unclear. STAT3 (signal transducer and activator of transcription 3) plays a key role in HDL-induced cardioprotection. In the heart, microRNAs (miRNAs) are involved in ischemia reperfusion injury...

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Detalles Bibliográficos
Autores principales: Pedretti, Sarah, Brulhart-Meynet, Marie-Claude, Montecucco, Fabrizio, Lecour, Sandrine, James, Richard W., Frias, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586303/
https://www.ncbi.nlm.nih.gov/pubmed/31220137
http://dx.doi.org/10.1371/journal.pone.0218432