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Assessment of reproducibility and biological variability of fasting and postprandial plasma metabolite concentrations using (1)H NMR spectroscopy

INTRODUCTION: It is crucial to understand the factors that introduce variability before applying metabolomics to clinical and biomarker research. OBJECTIVES: We quantified technical and biological variability of both fasting and postprandial metabolite concentrations measured using (1)H NMR spectros...

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Detalles Bibliográficos
Autores principales: Li-Gao, Ruifang, Hughes, David A., le Cessie, Saskia, de Mutsert, Renée, den Heijer, Martin, Rosendaal, Frits R., Willems van Dijk, Ko, Timpson, Nicholas J., Mook-Kanamori, Dennis O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586348/
https://www.ncbi.nlm.nih.gov/pubmed/31220183
http://dx.doi.org/10.1371/journal.pone.0218549