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A toolkit for studying cell surface shedding of diverse transmembrane receptors

Proteolysis of transmembrane receptors is a critical cellular communication mechanism dysregulated in disease, yet decoding proteolytic regulation mechanisms of hundreds of shed receptors is hindered by difficulties controlling stimuli and unknown fates of cleavage products. Notch proteolytic regula...

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Detalles Bibliográficos
Autores principales: Hayward, Amanda N, Aird, Eric J, Gordon, Wendy R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586460/
https://www.ncbi.nlm.nih.gov/pubmed/31172946
http://dx.doi.org/10.7554/eLife.46983