Cargando…
A toolkit for studying cell surface shedding of diverse transmembrane receptors
Proteolysis of transmembrane receptors is a critical cellular communication mechanism dysregulated in disease, yet decoding proteolytic regulation mechanisms of hundreds of shed receptors is hindered by difficulties controlling stimuli and unknown fates of cleavage products. Notch proteolytic regula...
Autores principales: | Hayward, Amanda N, Aird, Eric J, Gordon, Wendy R |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586460/ https://www.ncbi.nlm.nih.gov/pubmed/31172946 http://dx.doi.org/10.7554/eLife.46983 |
Ejemplares similares
-
A nanobody-based molecular toolkit provides new mechanistic insight into clathrin-coat initiation
por: Traub, Linton M
Publicado: (2019) -
Single methyl groups can act as toggle switches to specify transmembrane Protein-protein interactions
por: He, Li, et al.
Publicado: (2017) -
A novel fold for acyltransferase-3 (AT3) proteins provides a framework for transmembrane acyl-group transfer
por: Newman, Kahlan E, et al.
Publicado: (2023) -
Allosteric ligands control the activation of a class C GPCR heterodimer by acting at the transmembrane interface
por: Liu, Lei, et al.
Publicado: (2021) -
Mechanism of stepwise electron transfer in six-transmembrane epithelial antigen of the prostate (STEAP) 1 and 2
por: Chen, Kehan, et al.
Publicado: (2023)