Cooperation of mitochondrial and ER factors in quality control of tail-anchored proteins

Tail-anchored (TA) proteins insert post-translationally into the endoplasmic reticulum (ER), the outer mitochondrial membrane (OMM) and peroxisomes. Whereas the GET pathway controls ER-targeting, no dedicated factors are known for OMM insertion, posing the question of how accuracy is achieved. The m...

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Detalles Bibliográficos
Autores principales: Dederer, Verena, Khmelinskii, Anton, Huhn, Anna Gesine, Okreglak, Voytek, Knop, Michael, Lemberg, Marius K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586462/
https://www.ncbi.nlm.nih.gov/pubmed/31172943
http://dx.doi.org/10.7554/eLife.45506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586462/
https://www.ncbi.nlm.nih.gov/pubmed/31172943
http://dx.doi.org/10.7554/eLife.45506

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