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Cooperation of mitochondrial and ER factors in quality control of tail-anchored proteins
Tail-anchored (TA) proteins insert post-translationally into the endoplasmic reticulum (ER), the outer mitochondrial membrane (OMM) and peroxisomes. Whereas the GET pathway controls ER-targeting, no dedicated factors are known for OMM insertion, posing the question of how accuracy is achieved. The m...
Autores principales: | Dederer, Verena, Khmelinskii, Anton, Huhn, Anna Gesine, Okreglak, Voytek, Knop, Michael, Lemberg, Marius K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586462/ https://www.ncbi.nlm.nih.gov/pubmed/31172943 http://dx.doi.org/10.7554/eLife.45506 |
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