Cyclin D-CDK4 relieves cooperative repression of proliferation and cell cycle gene expression by DREAM and RB.

The Retinoblastoma protein (RB) restricts cell cycle gene expression and entry into the cell cycle. The RB-related protein p130 forms the DREAM (DP, RB-like, E2F and MuvB) complex and contributes to repression of cell cycle dependent genes during quiescence. Although both RB and DREAM bind and repre...

Descripción completa

Detalles Bibliográficos
Autores principales: Schade, Amy E., Oser, Matthew G., Nicholson, Hilary E., DeCaprio, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586519/
https://www.ncbi.nlm.nih.gov/pubmed/30833638
http://dx.doi.org/10.1038/s41388-019-0767-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586519/
https://www.ncbi.nlm.nih.gov/pubmed/30833638
http://dx.doi.org/10.1038/s41388-019-0767-9

Ejemplares similares