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Human Umbilical Tissue-Derived Cells Secrete Soluble VEGFR1 and Inhibit Choroidal Neovascularization

Exudative age-related macular degeneration (AMD), characterized by choroidal neovascularization (CNV), is the leading cause of irreversible blindness in developed countries. Anti-vascular endothelial growth factor (VEGF) drugs are the standard treatment for AMD, but they have limitations. Cell thera...

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Detalles Bibliográficos
Autores principales: Cao, Jing, Yang, Rong, Smith, Taylor E., Evans, Stephanie, McCollum, Gary W., Pomerantz, Steven C., Petley, Theodore, Harris, Ian R., Penn, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586593/
https://www.ncbi.nlm.nih.gov/pubmed/31276010
http://dx.doi.org/10.1016/j.omtm.2019.05.007