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Calaxin is required for cilia-driven determination of vertebrate laterality

Calaxin is a Ca(2+)-binding dynein-associated protein that regulates flagellar and ciliary movement. In ascidians, calaxin plays essential roles in chemotaxis of sperm. However, nothing has been known for the function of calaxin in vertebrates. Here we show that the mice with a null mutation in Efca...

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Detalles Bibliográficos
Autores principales: Sasaki, Keita, Shiba, Kogiku, Nakamura, Akihiro, Kawano, Natsuko, Satouh, Yuhkoh, Yamaguchi, Hiroshi, Morikawa, Motohiro, Shibata, Daisuke, Yanase, Ryuji, Jokura, Kei, Nomura, Mami, Miyado, Mami, Takada, Shuji, Ueno, Hironori, Nonaka, Shigenori, Baba, Tadashi, Ikawa, Masahito, Kikkawa, Masahide, Miyado, Kenji, Inaba, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586612/
https://www.ncbi.nlm.nih.gov/pubmed/31240264
http://dx.doi.org/10.1038/s42003-019-0462-y