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Regulating intracellular fate of siRNA by endoplasmic reticulum membrane-decorated hybrid nanoplexes

Most cationic vectors are difficult to avoid the fate of small interfering RNA (siRNA) degradation following the endosome-lysosome pathway during siRNA transfection. In this study, the endoplasmic reticulum (ER) membrane isolated from cancer cells was used to fabricate an integrative hybrid nanoplex...

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Detalles Bibliográficos
Autores principales: Qiu, Chong, Han, Hu-Hu, Sun, Jing, Zhang, Hai-Tao, Wei, Wei, Cui, Shi-He, Chen, Xin, Wang, Jian-Cheng, Zhang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586638/
https://www.ncbi.nlm.nih.gov/pubmed/31221991
http://dx.doi.org/10.1038/s41467-019-10562-w