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Regulating intracellular fate of siRNA by endoplasmic reticulum membrane-decorated hybrid nanoplexes
Most cationic vectors are difficult to avoid the fate of small interfering RNA (siRNA) degradation following the endosome-lysosome pathway during siRNA transfection. In this study, the endoplasmic reticulum (ER) membrane isolated from cancer cells was used to fabricate an integrative hybrid nanoplex...
Autores principales: | Qiu, Chong, Han, Hu-Hu, Sun, Jing, Zhang, Hai-Tao, Wei, Wei, Cui, Shi-He, Chen, Xin, Wang, Jian-Cheng, Zhang, Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586638/ https://www.ncbi.nlm.nih.gov/pubmed/31221991 http://dx.doi.org/10.1038/s41467-019-10562-w |
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