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Gene knockout analysis reveals essentiality of estrogen receptor β1 (Esr2a) for female reproduction in medaka

In vertebrates, sex steroids play crucial roles in multiple systems related to reproduction. In females, estrogens and their receptor estrogen receptor (ER or Esr) play indispensable roles in the negative sex steroid feedback regulation of pituitary gonadotropin secretion, which prevents excessive d...

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Detalles Bibliográficos
Autores principales: Kayo, Daichi, Zempo, Buntaro, Tomihara, Soma, Oka, Yoshitaka, Kanda, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586646/
https://www.ncbi.nlm.nih.gov/pubmed/31222039
http://dx.doi.org/10.1038/s41598-019-45373-y