The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism

Recent studies on mutations in cancer genomes have distinguished driver mutations from passenger mutations, which occur as byproducts of cancer development. The cancer genome atlas (TCGA) project identified 299 genes and 24 pathways/biological processes that drive tumor progression (Cell 173: 371-38...

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Detalles Bibliográficos
Autores principales: Chang, Soojeong, Yim, Sujin, Park, Hyunsung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586683/
https://www.ncbi.nlm.nih.gov/pubmed/31221981
http://dx.doi.org/10.1038/s12276-019-0230-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586683/
https://www.ncbi.nlm.nih.gov/pubmed/31221981
http://dx.doi.org/10.1038/s12276-019-0230-6

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