The sigma‐1 receptor behaves as an atypical auxiliary subunit to modulate the functional characteristics of Kv1.2 channels expressed in HEK293 cells

Expression of Kv1.2 within Kv1.x potassium channel complexes is critical in maintaining appropriate neuronal excitability and determining the threshold for action potential firing. This is attributed to the interaction of Kv1.2 with a hitherto unidentified protein that confers bimodal channel activa...

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Detalles Bibliográficos
Autores principales: Abraham, Madelyn J., Fleming, Kayla L., Raymond, Sophie, Wong, Adrian Y. C., Bergeron, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586770/
https://www.ncbi.nlm.nih.gov/pubmed/31222975
http://dx.doi.org/10.14814/phy2.14147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586770/
https://www.ncbi.nlm.nih.gov/pubmed/31222975
http://dx.doi.org/10.14814/phy2.14147

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