A universal fluorescence-based toolkit for real-time quantification of DNA and RNA nuclease activity

DNA and RNA nucleases play a critical role in a growing number of cellular processes ranging from DNA repair to immune surveillance. Nevertheless, many nucleases have unknown or poorly characterized activities. Elucidating nuclease substrate specificities and co-factors can support a more definitive...

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Detalles Bibliográficos
Autores principales: Sheppard, Emily C., Rogers, Sally, Harmer, Nicholas J., Chahwan, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586798/
https://www.ncbi.nlm.nih.gov/pubmed/31222049
http://dx.doi.org/10.1038/s41598-019-45356-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586798/
https://www.ncbi.nlm.nih.gov/pubmed/31222049
http://dx.doi.org/10.1038/s41598-019-45356-z

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